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Accueil du site > Membres associés > Mylène Aubertin
Le Dr Aubertin-Leheudre est titulaire d’un B.Sc. en Kinésiologie (2000) de l’université de Montpellier (France) et d’une M.Sc. en réadaptation à la santé (Kinésiologie, 2002) de l’université de Toulouse (France) ainsi qu’une M.Sc en kinanthropologie (2003) de l’université de Sherbrooke dont le sujet était rôle de l’exercice et des hormones de synthèse sur la composition corporelle des femmes ménopausées. Elle a obtenu son Ph.D. en Gérontologie (2006) à l’Université de Sherbrooke sur la thématique des phytoestrogènes et de l’exercice dans la prévention des risques cardiovasculaires chez la femme ménopausée obèse ou sarcopénique-obèse. Elle a ensuite poursuivi sa formation de chercheur par un stage postdoctoral de 2 ans (2009) au département de (...) >  suite


Le but de ma recherche est 1) de caractériser le profil métabolique et hormonal d’une nouvelle sous-population chez les personnes âgées soit les sarcopéniques-obèses ; et 2) de vérifier le rôle préventif de supplémentation ou d’un programme d’exercice dans les effets délétères causées par le développement de la sarcopénie-obésité. Les femmes sarcopéniques-obèses sont des personnes caractérisées par une faible masse musculaire appendiculaire (bras+ jambe 40%). Ces femmes représentent environ 15% de la population de femmes ménopausées. Ces individus sont prédisposés au développement plus important de perturbations métaboliques (ex. résistance à l’insuline, hypertension) qui peuvent par la suite augmenter leur risque de développer le diabète de type 2 et des maladies (...) >  suite


Publications récentes


Behavioral compensatory adjustment to exercise intervention.
Barbat-Artigas S, Aubertin-Leheudre M. (14 novembre 2011)

Relationship Between the Bertin Index to Estimate Visceral Adipose Tissue From Dual-Energy X-Ray Absorptiometry and Cardiometbolic Risk Factors Before and After Weight Loss.
Karelis AD, Rabasa-Lhoret R, Pompilus R, Messier V, Strychar I, Brochu M, Aubertin-Leheudre M. (25 août 2011)
The purpose of this study was to investigate the relationship between visceral adipose tissue (VAT), estimated with the Bertin index obtained from dual-energy X-ray absorptiometry (DXA), with cardiometabolic risk factors before and after a (...) suite

The metabolically healthy but obese postmenopausal woman presents a favourable heart rate variability profile.
Robillard ME, Bellefeuille P, Comtois AS, Aubertin-Leheudre M, Karelis AD. (4 juillet 2011)
Abstract Objective. The purpose of this study was to investigate the heart rate variability (HRV) profile in obese women displaying the metabolically healthy but obese (MHO) phenotype. Design. We studied 47 obese, sedentary postmenopausal women. (...) suite

Relationship between essential amino acids and muscle mass, independent of habitual diets, in pre- and post-menopausal US women.
Andrich DE, Filion ME, Woods M, Dwyer JT, Gorbach SL, Goldin BR, Adlercreutz H, Aubertin-Leheudre M. (16 mai 2011)
The purpose of this secondary analysis was to examine the relationship between protein and essential amino acids (EAAs) intake with the level of muscle mass (MM) independent of the diet. Twenty-one omnivores, 22 ovo-lacto-vegetarians and 20 (...) suite

Effects of tai chi training in dynapenic and nondynapenic postmenopausal women.
Barbat-Artigas S, Filion ME, Dupontgand S, Karelis AD, Aubertin-Leheudre M. (6 mai 2011)
OBJECTIVE : The purpose of the present study was to investigate the effects of a 12-week tai chi program in type I dynapenic and nondynapenic postmenopausal women. METHODS : Sixty-two postmenopausal women were recruited. Body composition, (...) suite

Relationship between dynapenia and cardiorespiratory functions in healthy postmenopausal women : novel clinical criteria.
Barbat-Artigas S, Dupontgand S, Fex A, Karelis AD, Aubertin-Leheudre M. (avril 2011)
OBJECTIVE : Muscle strength seems to be a better indicator of physical limitations than skeletal muscle mass is. The purpose of this study was to investigate, using a new developed clinical tool, the relationship between type I dynapenia and (...) suite

Menopause and sarcopenia : A potential role for sex hormones.
Messier V, Rabasa-Lhoret R, Barbat-Artigas S, Elisha B, Karelis AD, Aubertin-Leheudre M. (25 février 2011)
Menopause is associated with a decline in estrogen levels, which could lead to an increase in visceral adiposity as well as a decrease in bone density, muscle mass and muscle strength. This decline in muscle mass, known as sarcopenia, is (...) suite

Effects of soya isoflavones and exercise on body composition and clinical risk factors of cardiovascular diseases in overweight postmenopausal women : a 6-month double-blind controlled trial.
Choquette S, Riesco E, Cormier E, Dion T, Aubertin-Leheudre M, Dionne IJ. (17 décembre 2010)
Results from a pilot project indicate that isoflavones and exercise could have an additive effect on body composition and clinical risk factors of CVD in postmenopausal women. The objective of the present study was to assess the combined effect (...) suite

Comparison of sex hormonal and metabolic profiles between omnivores and vegetarians in pre- and post-menopausal women.
Karelis AD, Fex A, Filion ME, Adlercreutz H, Aubertin-Leheudre M. (9 mars 2010)
The purpose of the present study was to investigate the sex hormonal and metabolic profiles in vegetarians and compare these with the profiles in omnivores. The design of the present study was cross-sectional. The study sample of pre- and (...) suite

Fat mass threshold associated with a significant deterioration of insulin sensitivity in postmenopausal women.
Bobeuf F, Aubertin-Leheudre M, Lord C, Labonté M, Khalil A, Dionne IJ. (8 février 2010)
The aim of this study was to establish a cut-off value of percentage of fat mass (%FM) at which insulin sensitivity (IS) is significantly altered in sedentary postmenopausal women. Our results suggest that maintaining a %FM below 41% would (...) suite

Synergic effect of phytoestrogens and exercise training on cardiovascular risk profile in exercise-responder postmenopausal women : a pilot study.
Riesco E, Aubertin-Leheudre M, Maltais ML, Audet M, Dionne IJ. (2010)
OBJECTIVE : We showed that isoflavones and exercise improve total and abdominal fat mass (FM) to a greater extent than does exercise alone in postmenopausal women, but not other cardiovascular disease (CVD) risk factors. Fat-free mass (FFM) (...) suite

Plasma and urinary alkylresorcinol metabolites as potential biomarkers of breast cancer risk in Finnish women : a pilot study.
Aubertin-Leheudre M, Koskela A, Samaletdin A, Adlercreutz H. (2010)
Alkylresorcinols (ARs) are shown to be good biomarkers of consumption of rye and whole-grain wheat products in man. The aim of this pilot study was to investigate AR metabolites as potential biomarkers of breast cancer (BC) risk in Finnish women (...) suite

Plasma alkylresorcinol metabolites as potential biomarkers of whole-grain wheat and rye cereal fibre intakes in women.
(29 octobre 2009)
It has been demonstrated that intact plasma alkylresorcinols (AR) and urinary AR metabolites could be used as biomarkers of whole-grain intake. Thereafter, we developed the method for the plasma AR metabolites, which is more convenient and (...) suite

Relationship between animal protein intake and muscle mass index in healthy women.
Aubertin-Leheudre M, Adlercreutz H. (14 août 2009)
The amount and the type of dietary protein could play a role in determining the quantity of skeletal muscle mass. The aim was to examine the relationship between the type of protein intake and the level of muscle mass in healthy omnivorous and (...) suite

Fat/fiber intakes and sex hormones in healthy premenopausal women in USA.
Aubertin-Leheudre M, Gorbach S, Woods M, Dwyer JT, Goldin B, Adlercreutz H. (9 août 2009)
The mechanisms by which diet affects breast cancer (BC) risk are poorly understood but a positive relationship between fat and a negative association with fiber intake and BC risk have been demonstrated. Here we study the association between (...) suite

Isoflavones and clinical cardiovascular risk factors in obese postmenopausal women : a randomized double-blind placebo-controlled trial.
Aubertin-Leheudre M, Lord C, Khalil A, Dionne IJ. (14 septembre 2008)
AIMS : To investigate whether 6 months of isoflavone supplementation, which has been shown to be sufficient to improve menopausal symptoms, could also improve clinical cardiovascular disease (CVD) risk factors in obese postmenopausal women, (...) suite

Plasma alkylresorcinols and urinary alkylresorcinol metabolites as biomarkers of cereal fiber intake in Finnish women.
Aubertin-Leheudre M, Koskela A, Marjamaa A, Adlercreutz H. (2 septembre 2008)
Alkylresorcinols (AR) could be good biomarkers of consumption of fiber-rich cereal products. The aim of this study was to examine the relationship between plasma ARs or urinary AR metabolites and cereal fiber intake in women consuming their (...) suite

Quantification of alkylresorcinol metabolites in plasma by high-performance liquid chromatography with coulometric electrode array detection.
Koskela A, Samaletdin A, Aubertin-Leheudre M, Adlercreutz H. (9 août 2008)
This study presents the optimization and validation of a rapid protocol for quantifying alkyresorcinol (AR) metabolites 3,5-dihydroxybenzoic acid (DHBA) and 3-(3,5-dihydroxyphenyl)-1-propanoic acid (DHPPA) in plasma, using high-performance (...) suite

Enhanced rate of resting energy expenditure in women using hormone-replacement therapy : preliminary results.
Aubertin-Leheudre M, Goulet ED, Dionne IJ. (janvier 2008)
Hormone-replacement therapy (HRT) attenuates the menopause-associated alterations in body composition. It is not known, however, whether this effect is a result of a concomitant increase in energy expenditure. The authors examined whether women (...) suite

No difference in insulin sensitivity between healthy postmenopausal women with or without sarcopenia : a pilot study.
Goulet ED, Lord C, Chaput JP, Aubertin-Leheudre M, Brochu M, Dionne IJ. (27 avril 2007)
Insulin plays a pivotal role in skeletal muscle protein metabolism and its action decreases with age. A loss of muscle mass, termed sarcopenia, also occurs with age. The age-associated decline in insulin sensitivity (IS) may negatively alter (...) suite

Six months of isoflavone supplement increases fat-free mass in obese-sarcopenic postmenopausal women : a randomized double-blind controlled trial.
Aubertin-Leheudre M, Lord C, Khalil A, Dionne IJ. (21 février 2007)
OBJECTIVE : The aim of this study was to verify if six months of isoflavone supplementation could increase fat-free mass (FFM) and muscle mass index (MMI=appendicular FFM/height(2)) in obese-sarcopenic postmenopausal women. DESIGN : (...) suite

A meta-analysis of the effects of glycerol-induced hyperhydration on fluid retention and endurance performance.
Goulet ED, Aubertin-Leheudre M, Plante GE, Dionne IJ. (2007)
The authors determined, through a meta-analytic approach, whether glycerol-induced hyperhydration (GIH) enhances fluid retention and increases endurance performance (EP) significantly more than water-induced hyperhydration (WIH). Collectively, (...) suite

Is overweight/obesity associated with short sleep duration in older women ?
Chaput JP, Lord C, Aubertin-Leheudre M, Dionne IJ, Khalil A, Tremblay A. (2007)
BACKGROUND AND AIM : No study to date has documented the association between short sleep duration and the risk for obesity in older people. Therefore, the aim of this study was to examine cross-sectional associations between short sleep duration (...) suite

Dietary animal protein intake : association with muscle mass index in older women.
Lord C, Chaput JP, Aubertin-Leheudre M, Labonté M, Dionne IJ. (2007)
BACKGROUND : Aging is associated with reductions in muscle mass and strength, so-called sarcopenia, and is generally characterized using muscle mass index (MMI = FFM (kg)/height (m)2). It is believed that adequate nutrition especially regarding (...) suite

Effect of 6 months of exercise and isoflavone supplementation on clinical cardiovascular risk factors in obese postmenopausal women : a randomized, double-blind study.
Aubertin-Leheudre M, Lord C, Khalil A, Dionne IJ. (2007)
OBJECTIVE : To investigate whether 6 months of exercise combined with isoflavone supplementation could improve clinical risk factors that predispose to cardiovascular disease in obese postmenopausal women. DESIGN : This was a randomized, (...) suite

Relationship between antioxidant intakes and class I sarcopenia in elderly men and women.
Chaput JP, Lord C, Cloutier M, Aubertin Leheudre M, Goulet ED, Rousseau S, Khalil A, Dionne IJ. (2007)
BACKGROUND : The effect of nutritional intake on sarcopenia has been mostly examined in class II sarcopenia, i.e. when muscle mass has sufficiently decreased to induce a loss in physical capacity. Although this provides important information (...) suite


Équipe

  • Sébastien BARBAT, étudiant Ph.D.
  • Sophie DUPONTGAND, étudiante M.Sc.
  • Annie FEX, étudiante M.Sc.
  • Marie-Ève FILLION, étudiante M.Sc.

Contacts

Mylène AUBERTIN, Ph.D.

  • Professeure
  • Dépt. de Kinanthropologie,
    Université du Québec à Montréal,
    C.P. 8888, Succursale Centre-Ville, Montréal, Canada, H3C 3P8
  • Bureau : SB-4615
  • Tél. bureau : (514) 987-3000, poste 5018
  • Télécopieur : (514) 987-6616
  • Courriel
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